Publications by authors named "T Gambichler"
Background: Cancer immunotherapy has revolutionized melanoma treatment, but the high number of non-responders still emphasizes the need for improvement of therapy. One potential avenue for enhancing anti-tumor treatment is through the modulation of coagulation and platelet activity. Both have been found to play an important role in the tumor microenvironment, tumor growth and metastasis.
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- Herpes zoster (HZ) significantly impacts individual and public health, and a study analyzed clinical and laboratory data from 520 hospitalized HZ patients to identify key prognostic indicators.* ! -
- Results showed that systemic immune inflammatory biomarkers (like NLR and PIV) were much higher in HZ patients than healthy individuals, with absolute eosinopenia being a strong predictor for herpes zoster ophthalmicus (HZO).* ! -
- Key findings linked immunosuppression to a higher risk of herpes encephalitis and longer hospital stays, while not receiving intravenous antiviral therapy increased the likelihood of postherpetic neuralgia.* !
Background: Laboratory-based biomarkers accurately presenting systemic lupus erythematosus (SLE) disease activity may have a practical value in clinical routine. As shown in many other conditions, complete blood count (CBC)-derived biomarkers may also play a role in SLE.
Objectives: We aimed to study for the first time the pan-immune-inflammation value (PIV, monocytes x platelets x neutrophils/lymphocytes) and the more established systemic immune-inflammation index (SII, neutrophils x platelets /lymphocytes) in SLE patients and correlate it with serological and clinical findings including disease outcomes.