Publications by authors named "T G Olajide"
Africa, with 18.3% of the world's population, faces a significant research output gap, contributing only 2% of global research despite bearing a substantial disease burden. This discrepancy is partly due to inadequate research infrastructure, limited funding, and a shortage of physician-scientists.
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- HIV significantly affects neurocognitive function in Africa, leading to high prevalence rates of neurocognitive disorders, with Central and South Africa showing the highest impairment levels (around 49.33%).
- Variability in neurocognitive impairment prevalence is influenced by factors like ART availability, healthcare infrastructure, and co-infections, emphasizing the need for targeted interventions.
- Addressing this issue requires collaboration among healthcare providers, policymakers, and communities, focusing on education, early detection, improved resources, and research partnerships to better support individuals living with HIV.
This study investigated the effects of preheat treatment (70-100 °C) and syringic acid (SA) grafting on the antioxidant, antibacterial, and physicochemical properties of black soybean protein isolate (BSPI) before and after in vitro digestion. The results revealed that both preheat treatment and SA grafting increased the digestibility and the absolute zeta potential value of BSPI. However, as the preheating temperature increased, the antioxidant ability of BSPI decreased, which was improved by SA grafting.
View Article and Find Full Text PDFMetastatic cancer cells traverse constricted spaces that exert forces on their nucleus and the genomic contents within. Cancerous tumors are highly heterogeneous and not all cells within them can achieve such a feat. Here, we investigated what initial genome architecture characteristics favor the constricted migratory ability of cancer cells and which arise only after passage through multiple constrictions.
View Article and Find Full Text PDFParkinson's disease (PD) is a prevalent neurodegenerative disease marked by dopaminergic neuronal loss and misfolded alpha-synuclein (α-syn) accumulation, which results in both motor and cognitive symptoms. Its occurrence grows with age, with a larger prevalence among males. Despite substantial study, effective medicines to reduce or stop the progression of diseases remain elusive.
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