Aggressive anticancer treatment in the last 2 weeks of life.

Background: There is a concern that terminally ill cancer patients may be aggressively treated due to the rapidly growing possibilities of anticancer treatment. The aim of this study was to evaluate the use of anticancer treatment at the end of life (EoL).

Materials And Methods: This retrospective study included adult patients with advanced solid cancers who were treated at the Institute of Oncology Ljubljana and died of cancer between January 2015 and December 2019.

Breast cancer risk prediction using Tyrer-Cuzick algorithm with an 18-SNPs polygenic risk score in a European population with below-average breast cancer incidence.

Goals: To determine whether an 18 single nucleotide polymorphisms (SNPs) polygenic risk score (PRS18) improves breast cancer (BC) risk prediction for women at above-average risk of BC, aged 40-49, in a Central European population with BC incidence below EU average.

Methods: 502 women aged 40-49 years at the time of BC diagnosis completed a questionnaire on BC risk factors (as per Tyrer-Cuzick algorithm) with data known at age 40 and before BC diagnosis. Blood samples were collected for DNA isolation.

Probabilistic Fingermark Quality Assessment with Quality Region Localisation.

The assessment of fingermark (latent fingerprint) quality is an intrinsic part of a forensic investigation. The fingermark quality indicates the value and utility of the trace evidence recovered from the crime scene in the course of a forensic investigation; it determines how the evidence will be processed, and it correlates with the probability of finding a corresponding fingerprint in the reference dataset. The deposition of fingermarks on random surfaces occurs spontaneously in an uncontrolled fashion, which introduces imperfections to the resulting impression of the friction ridge pattern.

Rehabilitation of COVID-19 patients with respiratory failure and critical illness disease in Slovenia: an observational study.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection often causes pneumonia and respiratory failure that may lead to postintensive care syndrome, including critical illness neuropathy (CIN) and critical illness myopathy (CIM). The data on the rehabilitation outcomes of post-novel coronavirus disease (COVID) patients with CIN and CIM following respiratory failure and mechanical ventilation are still limited. To address this, we enrolled in our prospective observational study a sample of 50 consecutive COVID-19 patients admitted to our facility between 2 November 2020 and 3 May 2021 with electrophysiologically confirmed or clinically suspected diagnosis of CIN/CIM.