Publications by authors named "T G Nygaard"
() is a prominent Gram-positive bacterial pathogen that expresses numerous cytotoxins known to target human polymorphonuclear leukocytes (PMNs or neutrophils). These include leukocidin G/H (LukGH, also known as LukAB), the Panton-Valentine leukocidin (PVL), γ-hemolysin A/B (HlgAB), γ-hemolysin B/C (HlgBC), leukocidin E/D (LukED), α-hemolysin (Hla), and the phenol-soluble modulin-α peptides (PSMα). However, the relative contribution of each of these cytotoxins in causing human PMN lysis is not clear.
View Article and Find Full Text PDFThe accurate localization of electroencephalography (EEG) electrode positions is crucial for accurate source localization. Recent advancements have proposed alternatives to labor-intensive, manual methods for spatial localization of the electrodes, employing technologies such as 3D scanning and laser scanning. These novel approaches often integrate magnetic resonance imaging (MRI) as part of the pipeline in localizing the electrodes.
View Article and Find Full Text PDFOral versus intravenous empirical antibiotics in children and adolescents with uncomplicated bone and joint infections: a nationwide, randomised, controlled, non-inferiority trial in Denmark.
Lancet Child Adolesc Health
September 2024
Article Synopsis
- - This study explored whether starting treatment for bone and joint infections (BJIs) in children with oral antibiotics is as effective and safe as beginning with intravenous (IV) antibiotics, which are often more expensive and burdensome.
- - Conducted in Denmark from September 2020 to June 2023, the trial involved children aged 3 months to 17 years and compared high-dose oral antibiotics (amoxicillin/clavulanic acid or dicloxacillin) to IV ceftriaxone, with strict inclusion and exclusion criteria to ensure appropriate patient selection.
- - The main goal was to assess any lasting complications in mobility or function after six months, determining that if the risk difference in negative outcomes between the two treatment methods
Robots operating in the real world will experience a range of different environments and tasks. It is essential for the robot to have the ability to adapt to its surroundings to work efficiently in changing conditions. Evolutionary robotics aims to solve this by optimizing both the control and body (morphology) of a robot, allowing adaptation to internal, as well as external factors.
View Article and Find Full Text PDFBackground and purpose - We noted several adverse events in patients in whom the first version of the STRYDE limb-lengthening nail (NuVasive Specialized Orthopaedics, San Diego, CA) had been implanted. Pain, osteolysis, periosteal reactions, and cortical hypertrophy at the nail junction were noted. Here, we present the analysis of 23 retrieved STRYDE implants.
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