[Thrombogenicity of the arterioles and venules in experimental tumor growth].

The authors studied laser radiation induced thrombogenesis in microvessels--arterioles and venules--of the mesentery of tumor-carrier rats. Statistically significant increase of thrombogenic potential was revealed in the venules on the 7th day after reinoculation of Pliss' lymphosarcoma, and only a tendency to its increase in the arteries. At the same time an increase was noted of the aggregation activity of blood platelets and inhibition of their deaggregation.

[Systemic arterial pressure and characteristics of its changes in response to hypertensive agents in tumor-bearing animals].

Arterial pressure (in the carotid artery determined by electromanometry) and total peripheral resistance (changes in the clear space of resistive arteries of the mesenterium, skeletal muscles and mammary glands measured by biotelemicroscopy) were studied in tumor-bearing animals (random bred, BALB/c and CBA mice with Ehrlich carcinoma). With the growth of hypodermic injected tumor, it has been shown that the arterial pressure first dropped and then there was a tendency towards normalization, but the pressure never reached the initial level. At the same time arterial dilatation took place, especially at the first stage of tumor growth.