[Hepatocellular mechanisms of compensatory processes influenced by environmental chemical factors].

The hepatocellular compensatory mechanisms against chemical pollutants were investigated. They expressed in hypertrophic nucleus-nucleolus structures, increased DNA-synthetizing and proliferative activity of hepatocytes, activated hepatic bile secretion and metabolic rearrangement in hepatocytes.

[Methodological approaches to the morphological assessment of the skin under slight toxic effects].

One-fold treatment of rat skin with 3% water solution of potassium bichromate resulted in slight toxic effects in epidermocytes, sebaceous gland cells and epithelial follicles. System of indexes for the slight toxic effects to assess was worked up.

[Structural and functional changes in the liver of pregnant rats and their fetuses exposed to cadmium, benzol and lead nitrate].

Lead nitrate administered to noninbred rats with drinking water on the level of IO MAC (0.3 mg/l) during the whole period of gestation lead to the strengthening of hepatotoxic effect of cadmium chloride (7.5 and 15 mg/kg daily by gavage from the 1st to 20th day of gestation), manifest in significant increase of the hepatocytes alteration index, increase of the number of the pyknotic cells of reticuloendothelial system, increase of the degree of dams' liver hepatocytes dystrophy, decrease in the specific volume of megakaryocytes in the liver of their fetuses.

[Hygienic evaluation of mineralizing lime substances for correction of mineral composition of low-mineral drinking water].

4 out of 6 mineralizing lime materials that were studied have been recommended for the practical application with the aim to correct the mineral composition of drinking low-mineralized water. The possibility to predict the biological properties of multicomponent mineralizing materials has been established on the basis of results of analysis of their chemical composition.