Publications by authors named "T G Hurley"
Aim: Immune dysregulation and delayed onset of sleep wake cycling (SWC) are associated with worse outcome in neonatal encephalopathy (NE), however the association between sleep and immune dysfunction in NE remains unclear. Aimed to evaluate association of sleep and systemic inflammation with outcomes in NE.
Methods: Amplitude-integrated electroencephalography (aEEG) recordings were collected on infants undergoing therapeutic hypothermia (TH).
Article Synopsis
- Neonatal encephalopathy (NE) is a serious condition impacting newborns, where therapeutic hypothermia is the standard treatment, yet many still face long-term issues; the paper aims to create a Core Outcome Set (COS) for consistent reporting in studies.* -
- A systematic review of 116 papers identified 386 reported outcomes from NE studies, categorized into 18 domains, highlighting a lack of uniformity as no single outcome was universally reported across studies.* -
- The findings emphasize the need for standardized outcome measures, including family input, to improve the comparison of treatments and enhance research on NE.*
This work introduces a novel method of recovering bioactive berry natural products (BNPs) using solid phase extraction with metal-organic frameworks (MOF-SPE). Two pyrene-based MOFs with different structural topologies, Al-PyrMOF and Zr-NU-1000, were evaluated for their ability to capture and desorb BNPs, including ellagic acid, quercetin, gallic acid, and p-coumaric acid. Time-dependent BNP uptake via dispersive SPE revealed that NU-1000 outperformed Al-PyrMOF in capturing all BNPs.
View Article and Find Full Text PDFXenon (Xe) is a commercially valuable element found in trace amounts in the off-gas from used nuclear fuel. Recovering Xe from these streams provides a cost-effective means to increase its supply. However, achieving high-purity Xe recovery is challenging due to the need for separation from nearly identical krypton (Kr).
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