Publications by authors named "T G Guiguemde"
Article Synopsis
- - Histoplasmosis is a fungal infection caused by Histoplasma capsulatum, and this study reviews its epidemiological, clinical, diagnostic, and treatment aspects over the past 30 years through a comprehensive literature search.
- - Between 1992 and 2021, 190 publications reported 212 cases of histoplasmosis, with a significant increase in cases noted in the last decade, particularly in 2020, and disseminated forms being more common than localized ones in both American and African cases.
- - Itraconazole and Amphotericin B are the most frequently used treatments, and while American histoplasmosis is found globally, African histoplasmosis is mainly present in intertropical Africa; there is a
Schistosomiasis is a common neglected helminthic disease in the tropics and sub-tropics particularly in sub-Saharan countries including Burkina Faso. It is the second world parasitic endemic disease after malaria. The two prevalent species infecting human in Burkina Faso are are Schistosoma haematobium and Schistosoma mansoni which cause respectively the urogenital schistosomiasis and the intestinal schistosomiasis.
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- Intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in pregnant women is crucial in Burkina Faso, but resistance to the drug needs further investigation due to insufficient data on genetic mutations.
- A study conducted from April 2019 to March 2020 analyzed placentas from postpartum women in Ouagadougou to assess genetic diversity and mutation prevalence in malaria-causing parasites.
- Findings revealed high rates of PCR-positive samples, widespread allelic families, and certain genetic mutations, indicating potential early warning signs for increasing resistance to sulfadoxine-pyrimethamine in the population.
Article Synopsis
- Pregnant women are highly susceptible to intestinal parasitoses, warranting regular surveys for better epidemiological data on these infections in vulnerable populations.
- A study conducted in Burkina Faso from February to April 2015 analyzed 315 stool samples from pregnant women, revealing a high prevalence of 66.7% for intestinal parasitosis, predominantly caused by protozoa (66.0%).
- The findings suggest a need for treatment strategies like administering metronidazole, alongside sulfadoxine-pyrimethamine, to effectively tackle these infections in pregnant women.
Background: To strengthen the fight against malaria, it is imperative to identify weaknesses and possible solutions in order to improve programmes implementation. This study reports experiences gained from collaboration between decision-makers and researchers from a World Bank project (Malaria and Neglected Tropical Diseases in the Sahel, SM/NTD). The objectives of this paper were to identify bottlenecks in malaria programme implementation as well as related research questions they bring up.
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