Publications by authors named "T G Fetsych"

Ovarian cancer (OC) represents the most lethal malignancy in gynaecologic oncology practice and shows a high recurrence rate due to its early chemoresistance to first-line chemotherapy. Yet, timely selection of the correct treatment strategy is likely to prolong a patient's survival. MicroRNAs (miRNAs) are a class of short non-coding RNAs responsible for the expression of 30%-60% of human genes.

View Article and Find Full Text PDF

Background And Objectives: Clinical experience in Western Europe suggests that cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are promising methods in the management of gastric cancer (GC) with peritoneal metastases. However, there are almost no data on such treatment results in patient from Central-Eastern European population.

Methods: A retrospective cooperative study was performed at 6 Central-Eastern European HIPEC centers.

View Article and Find Full Text PDF

Background And Objectives: Clinical experience suggests that cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) play an important role in the management of ovarian cancer. In order to improve patient selection, the peritoneal surface disease severity score (PSDSS) was previously introduced for use in colorectal cancer patients. However, almost no data exist regarding the utility of the PSDSS index in ovarian cancer patients.

View Article and Find Full Text PDF

The amount of lymph node dissection (LD) required during surgical treatment of gastric cancer surgery has been quite controversial. In the 1970s and 1980s, Japanese surgeons developed a doctrine of aggressive preventive gastric cancer surgery that was based on extended (D2) LD volumes. The West has relatively lower incidence rates of gastric cancer, and in Europe and the United States the most common LD volume was D0-1.

View Article and Find Full Text PDF

The risk factors for peritoneal carcinomatosis (PC) occurrence after radical surgical treatment of patients, suffering colorectal cancer, were analyzed. Probability of the disease recurrence occurrence have depended upon a patient's age, the invasion depth of primary tumor, its histological type and differentiation degree. Determination of independent predictors gives possibility to prognosticate the PC individually and to diagnose it early.

View Article and Find Full Text PDF