[Case of a Pleomorphic Carcinoma Successfully Treated with Nivolumab and Ipilimumab].

A 70-year-old man was referred to our hospital for an abnormal chest X-ray shadow. A chest CT scan showed a mass shadow with a cavitary lesion in segment 6 of the right lung. One year after radical resection(resection of the lower lobe of the right lung; pT2aN0M0, pStage ⅠB), the patient exhibited enlarged mediastinal lymph nodes and liver metastases, and postoperative recurrence was determined.

A Case of Squamous Cell Carcinoma of the Breast Occurring in Benign Phyllodes Tumor.

A 49-year-old woman visited our hospital after noticing an enlarged left breast mass. After a biopsy, she was diagnosed with fibroadenoma and underwent tumor resection. Postoperative pathology revealed squamous cell carcinoma (SCC) within a benign phyllodes tumor.

Sarcomere gene variants did not improve cardiac function in pediatric patients with dilated cardiomyopathy from Japanese cohorts.

Dilated cardiomyopathy (DCM) is a progressive myocardial disorder characterized by impaired cardiac contraction and ventricular dilation. However, some patients with DCM improve when experiencing left ventricular reverse remodeling (LVRR). Currently, the detailed association between genotypes and clinical outcomes, including LVRR, particularly among children, remains uncertain.

Stereotactic arrhythmia radioablation for ventricular tachycardia: a review of clinical trials and emerging roles of imaging.

Ventricular tachycardia (VT) is a severe arrhythmia commonly treated with implantable cardioverter defibrillators, antiarrhythmic drugs and catheter ablation (CA). Although CA is effective in reducing recurrent VT, its impact on survival remains uncertain, especially in patients with extensive scarring. Stereotactic arrhythmia radioablation (STAR) has emerged as a novel treatment for VT in patients unresponsive to CA, leveraging techniques from stereotactic body radiation therapy used in cancer treatments.

The Relationship of Pitch Discrimination with Segregation of Tonal and Speech Streams for Cochlear Implant Users.

Cochlear implant (CI) users often complain about music appreciation and speech recognition in background noise, which depend on segregating sound sources into perceptual streams. The present study examined relationships between frequency and fundamental frequency (F0) discrimination with stream segregation of tonal and speech streams for CI users and peers with no known hearing loss. Frequency and F0 discrimination were measured for 1,000 Hz pure tones and 110 Hz complex tones, respectively.