Publications by authors named "T Fujimori"
Article Synopsis
- The study conducted a retrospective analysis comparing the outcomes of revision posterior lumbar interbody fusion (PLIF) surgery to primary PLIF surgery, using data from patients who had previously undergone laminotomy.
- A total of 16 patients who had revision surgery and 61 patients who had primary surgery were assessed using the Zurich Claudication Questionnaire (ZCQ) for symptom severity and physical function before and after the surgeries.
- Both groups showed significant improvements in clinical outcomes after two years, with no statistically significant differences between them, indicating that revision PLIF may provide outcomes comparable to those of primary PLIF.
High jump is a power-demanding motor task. Jumpers extend the take-off leg joints with maximum effort, but kinetic requirements (i.e.
View Article and Find Full Text PDFBackground: Nonunion following fracture treatment remains a significant clinical challenge, adversely affecting the patient's quality of life and imposing a substantial economic burden. The emergence of bone morphogenetic protein 2 (BMP-2) for bone regeneration represents a promising avenue, albeit limited by side effects such as inflammatory reactions primarily due to suboptimal drug delivery systems. This study focuses on NOVOSIS putty (NP), a novel biomaterial designed for the sustained release of BMP-2, aiming to mitigate these limitations and enhance bone healing.
View Article and Find Full Text PDFEstablishing the correct kinetochore-microtubule attachment is crucial for faithful chromosome segregation. The kinetochore has various regulatory mechanisms for establishing correct bipolar attachment. However, how the regulations are coupled is not fully understood.
View Article and Find Full Text PDFArticle Synopsis
- * Studies show that the loss of the Men1 protein in osteoblasts leads to structural bone changes similar to those observed in osteoporosis patients, characterized by decreased bone-forming and increased bone-resorbing activities.
- * The research suggests that loss of Men1 triggers cellular senescence via mTORC1 activation and AMPK suppression, with potential treatment benefits from metformin, indicating a new avenue for therapeutic strategies against age-related osteoporosis.