Variation in stereoacuity: normative description, fixation disparity, and the roles of aging and gender.

Purpose: Variation in stereoacuity was examined in a large group of observers with Snellen acuity of 20/30 or less.

Methods: Threshold retinal disparity for 2.78 degrees x 2.

Suppressive rod-cone interactions: evidence for separate retinal (temporal) and extraretinal (spatial) mechanisms in achromatic vision.

We investigated the influence of selective rod light and dark adaptation on cone-mediated sensitivity to monocular displays modulated sinusoidally in both spatial and temporal domains. Rod light adaptation (1) increased sensitivity to high spatial frequencies [> or = 8 cycles per degree (cpd)] flickered slowly (< or = 2 Hz), an effect that we refer to as grating suppressive rod-cone interaction (gSRCI); (2) increased sensitivity to low spatial frequencies (< or = 2 cpd) flickered rapidly (> or = 8 Hz), an effect that we refer to as flicker suppressive rod-cone interaction (fSRCI); and (3) had relatively little influence on intermediate temporal-spatial-frequency combinations. The magnitudes of both gSRCI and fSRCI increased as the retinal position of the test display was increasingly displaced parafoveally.

Functional role of GABA in cat retina: II. Effects of GABAA antagonists.

Putative GABAergic mechanisms were studied in the cat retina by exogenous application of the GABAA antagonists picrotoxin (PTX), native bicuculline (BCC), and bicuculline methyl bromide (BCC MeBr). When recording intracellular responses from horizontal cells (HCs) and amacrine cells as well as electroretinograms (ERGs), drugs were added to the perfusate used to maintain the isolated eyecup; when recording extracellular spikes from ganglion cells of anesthetized cats, drugs were introduced by iontophoretic injection. Both PTX and BCC MeBr had relatively little influence upon the response properties of HCs.

Functional role of GABA in cat retina: I. Effects of GABAA agonists.

Putative GABAergic mechanisms were studied in perfused cat retina by means of intracellular recording and application of GABA and the GABAA agonists delta-amino valeric acid (dAVA), muscimol, and THIP. In contrast to results reported previously for cold-blooded vertebrates, introduction of 20 mM GABA into the superfusate had no influence upon the response properties of cat retinal horizontal cells (HCs). In common with results reported in cold-blooded vertebrates, introduction of the GABAA agonists dAVA (2-12 mM) and THIP or muscimol (0.

Tonic interocular suppression, binocular summation, and the visual evoked potential.

Purpose: Psychophysical studies have shown that a dark-adapted eye exerts a tonic interocular suppression (TIS) upon spatial vision mediated by the contralateral eye. The present study was designed to demonstrate TIS by means of visual evoked potential (VEP) procedures.

Methods: Evoked cortical potentials were obtained in response to reversing checkerboard patterns with fundamental Fourier frequencies between 3 and 12 cycles per degree.