Visualizing C-Labeled Metabolites in Maize Root Tips with Mass Spectrometry Imaging.

Tracing isotope-labeled metabolites has been used to study metabolic pathways or flux analysis. However, metabolic differences between the cells have been often ignored in these studies due to the limitation of solvent-based extraction. Here we demonstrate that the mass spectrometry imaging of isotope-labeled metabolites, referred to as MSI, can provide important insights into metabolic dynamics with cellular resolution that may supplement the traditional metabolomics and flux analysis.

Predicting Fingerprint Age Based on Ozonolysis Kinetics of Unsaturated Triacylglycerol Degradation.

Answering the question, "How old is a fingerprint?", is a highly sought-after aim in forensic science. Despite several decades of studies to find an empirical correlation in fingerprint aging, there has been no reliable method so far. In this study, we attempt to determine the time since deposition (TSD) of aged fingerprints from the chemical profile captured within a matrix-assisted laser desorption/ionization mass spectrometry data set.

Informed consent for image-guided procedures: a nationwide survey of perceptions and current practices.

Aim: To characterise the current landscape of informed consent practices for image-guided procedures, including location of consent, guideline availability, and utility of decision-aid resources.

Materials And Methods: A survey of 159 interventional radiologists was conducted from April through June 2022. The survey evaluated participant demographics (gender, practice type, and level of training) and consent practices.

On-tissue chemical derivatization of volatile metabolites for matrix-assisted laser desorption/ionization mass spectrometry imaging.

Mass spectrometry imaging (MSI) of volatile metabolites is challenging, especially in matrix-assisted laser desorption/ionization (MALDI). Most MALDI ion sources operate in vacuum, which leads to the vaporization of volatile metabolites during analysis. In addition, tissue samples are often dried during sample preparation, leading to the loss of volatile metabolites even for other MSI techniques.