Publications by authors named "T Florin"
Alternative antibiotic selections during the 2022 amoxicillin shortage in the US.
J Pediatric Infect Dis Soc
December 2024
This study of seven pediatric hospitals identified that the amoxicillin shortage in 2022 resulted in a decline in amoxicillin suspension prescribing by 30.8% with increases in use of amoxicillin non-suspension (+7.9) and broad-spectrum antibiotics.
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- The study aims to identify pediatric physicians' thresholds for conducting chest radiographs and prescribing antibiotics in cases of community-acquired pneumonia (CAP) in children, emphasizing the importance of these thresholds in clinical prediction model implementation.* -
- A survey was conducted with 208 pediatric emergency physicians who assessed 8 clinical vignettes and indicated their decisions regarding chest radiographs and antibiotic treatments, both before and after being informed of a validated prediction model's estimated probabilities for CAP.* -
- Results showed that knowledge of the prediction model led to lower thresholds for both testing (from 17.6% to 13.5%) and treatment (from 66.1% to 58.0%), suggesting the potential for integrating these thresholds into future
Article Synopsis
- The study examines the effectiveness of antibiotics in treating pediatric pneumonia in children and adolescents, specifically comparing outcomes for those who received antibiotics versus those who did not.
- Data was collected from a multistate claims database for Medicaid-insured individuals under 17 years old who were diagnosed with pneumonia between 2017 and 2019, taking into account factors to minimize bias.
- Results showed that treatment failure rates were slightly higher in children who did not receive antibiotics (10.7%) compared to those who did (8.7%), although the difference was not clinically significant.
Background: The MeMed BV Test produces a score that increases with increasing likelihood of bacterial infection. We evaluated its association with radiographic pneumonia in children.
Methods: We performed a secondary analysis of a multicenter prospective study of febrile children 90 days to 18 years presenting to an emergency department.