Publications by authors named "T Fleck"

Background: Covered stent correction for a sinus venosus atrial septal defect (SVASD) was first performed in 2009. This innovative approach was initially viewed as experimental and was reserved for highly selected patients with unusual anatomic variants. In 2016, increasing numbers of procedures began to be performed, and in several centers, it is now offered as a standard of care option alongside surgical repair.

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Background:  Extracorporeal membrane oxygenation (ECMO) can influence pharmacokinetics. We investigated the vancomycin dosage in children on ECMO compared to critically ill children to determine the necessary dosage adjustment on ECMO.

Methods:  Eight-year, single-center, retrospective cohort study at a tertiary heart center's pediatric cardiac intensive care unit (ICU) of children undergoing ECMO support.

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Article Synopsis
  • This study investigates the epidemiology of pediatric chronic heart failure (CHF) in Germany using healthcare claims data from nearly 4.8 million insured members between 2016 and 2021.* -
  • The prevalence of CHF among children was reported at 20.6 per 100,000 in 2016, slightly decreasing to 19.4 per 100,000 in 2021, with about 47% to 58% of these children experiencing annual hospitalizations.* -
  • Findings indicate that most CHF patients have serious comorbidities and that treatments include various medications and surgical options, while mortality rates among these children remain low, at less than 5 deaths annually.*
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Material extrusion (MEX) additive manufacturing has successfully fabricated assembly-free structures composed of different materials processed in the same manufacturing cycle. Materials with different mechanical properties can be employed for the fabrication of bio-inspired structures (i.e.

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Background:  Hypothermia is a neuroprotective strategy during cardiopulmonary bypass. Rewarming entailing a rapid rise in cerebral metabolism might lead to secondary neurological sequelae. In this pilot study, we aimed to validate the hypothesis that a slower rewarming rate would lower the risk of cerebral hypoxia and seizures in infants.

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