Publications by authors named "T Fehr"

Article Synopsis
  • JC-polyomavirus-associated nephropathy (JC-PVAN) is a rare condition impacting kidney transplant functions, with limited documented cases.
  • Two cases were presented involving patients who developed JC-PVAN more than five years after their kidney transplants, showing specific kidney damage during biopsies.
  • Despite initiating immunosuppressive therapy, both cases experienced a continued decline in kidney function, highlighting the need for thorough diagnostics when graft dysfunction occurs long after transplantation.
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Article Synopsis
  • * Mutations in this gene are linked to hamartoma tumor syndrome, leading to various disorders, including Bannayan-Riley-Ruvalcaba and Cowden syndromes.
  • * A recent case study describes a man in his late 20s with a PTEN mutation, who developed lupus nephritis, indicating a possible connection between the mutation and immune system dysregulation.
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The exploration of functional resting-state brain developmental parameters and measures can help to improve scientific, psychological, and medical applications. The present work focussed on both traditional approaches, such as topographical power analyses at the signal space level, and advanced approaches, such as the exploration of age-related dynamics of source space data. The results confirmed the expectation that the third life decade would show a kind of stability in oscillatory signal and source-space-related parameters.

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Background: The mammalian target of rapamycin (mTOR) inhibitors in combination with calcineurin inhibitors (CNIs), antimetabolites and corticosteroids for immunosuppression after lung transplantation (TPL) have gained importance in patients with chronic kidney disease (CKD). The goal of this study was to characterize lung transplant recipients (LTR) treated with mTOR inhibitors, with a special focus on kidney function.

Methods: LTR transplanted at the University Hospital Zurich between December 1992 and April 2022 were analyzed.

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Aims Of The Study: Systemic amyloidoses are rare protein-folding diseases with heterogeneous, often nonspecific clinical presentations. To better understand systemic amyloidoses and to apply state-of-the-art diagnostic pathways and treatment, the interdisciplinary Amyloidosis Network was founded in 2013 at University Hospital Zurich. In this respect, a registry was implemented to study the characteristics and life expectancy of patients with amyloidosis within the area covered by the network.

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