Publications by authors named "T F Slater"
Modern microscopy systems allow researchers to generate large volumes of image data with relative ease. However, the challenge of analyzing these data effectively is often hindered by a lack of computational skills. This bottleneck negatively impacts both research reproducibility and efficiency, as researchers frequently rely on manual or semi-automated analysis methods.
View Article and Find Full Text PDFAims: To design a regional clinical service for people with early-onset type 2 diabetes (EOT2D) in Leicester, Leicestershire and Rutland (England).
Methods: A literature search was undertaken to identify important considerations. A working group of key stakeholders was formed to design a triage system and service pathway.
Pt nanoparticles (diameter <3 nm), generated by metal vapor synthesis and supported on a high surface area carbon, were used to catalyze the aerobic oxidation of ethylene glycol to glycolic acid (GA) in water under neutral and basic reaction conditions. Controlled heat treatment of the catalyst under a nitrogen atmosphere brought about the formation of a morphologically well-defined catalyst. A combination of atomic resolution electron microscopy, CO stripping voltammetry, and XPS analyses conducted on as-synthesized and heat-treated catalysts demonstrated the crucial role of the nanoparticles' morphology on the stabilization of catalytically highly active Pt-OH surface species, which were key species for the Pt-catalyzed oxidation of the alcohol to the carbonyl functionality.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to investigate the incidence and rates of sleep disorders over five years in younger adults (16-≤40 years) and middle-older adults (≥40 years) with and without newly diagnosed type 2 diabetes.
- The results showed that individuals with type 2 diabetes had a significantly higher risk of developing sleep disorders compared to those without, with 14.2% of younger and 18.5% of middle-older adults affected.
- The findings suggest that while middle-older adults had a higher absolute risk, younger adults exhibited greater relative rates of sleep disorders, indicating the need for integrated sleep assessments in diabetes management, especially for those aged 40 and under.
We aimed to describe the safety and tolerability of initiation of sodium-glucose cotransporter 2 inhibitors (SGLT2i) during hospitalisation with heart failure, and the frequency of, and reasons for, subsequent discontinuation. In total, 934 patients who were not already prescribed a SGLT2i were hospitalised with heart failure, 77 (8%) were initiated on a SGLT2i a median of five (3-8.5) days after admission and two (0.
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