Marchiafava-Bignami Disease: A Case Report of a Reversible Cause of Dementia.

Marchiafava-Bignami disease (MBD) is a rare neurological disorder predominantly associated with chronic alcohol use, characterized by demyelination and necrosis of the corpus callosum. The condition often presents with cognitive dysfunction, motor deficits, and altered consciousness, which can range from mild confusion to severe stupor. Early recognition and treatment are crucial for improving outcomes.

Higher frequency of interstate over international transmission chains of SARS-CoV-2 virus at the Rio Grande do Sul - Brazil state borders.

Brazil's COVID-19 response has faced challenges due to the continuous emergence of variants of concern (VOCs), emphasizing the need for ongoing genomic surveillance and retrospective analyses of past epidemic waves to reassess and fine tune containment protocols. Rio Grande do Sul (RS), Brazil's southernmost state, has international borders and trades with Argentina and Uruguay, along with significant domestic connections within Brazil. The identification of source and sink transmission chains at national and international scales can identify main hubs and pathways to target future interventions.

Renal cell carcinoma with inferior vena cava thrombus: Survival and prognostic factors in surgically treated patients.

Introduction: Renal cell carcinoma (RCC) often develops a tumor thrombus extending into the inferior vena cava (IVC). Radical nephrectomy with IVC thrombectomy is the standard treatment, although prognostic factors are yet to be properly established.

Objectives: The objectives of this study were to review the clinicopathological features of surgically treated patients with RCC and IVC thrombus and to investigate potential prognostic factors.