Publications by authors named "T F Lawerman"
Article Synopsis
- - The study aimed to assess how accurately early-onset ataxia (EOA) can be recognized compared to conditions like developmental coordination disorder (DCD) and central hypotonia, using scientifically validated features.
- - Researchers analyzed 32 children with diagnoses of EOA, DCD, and hypotonia through videotaped assessments by three neurologists, focusing on inter-observer agreement and phenotypic profiles using a specific scoring system.
- - Results indicated that while EOA could be reliably distinguished from central hypotonia, it was not easily differentiated from DCD, highlighting that incorporating scientifically validated EOA features improved consensus on diagnoses.
Background: During childhood, many conditions may impact coordination. Examples are physiological age-related development and pathological conditions, such as early onset ataxia and developmental coordination disorder. These conditions are generally diagnosed by clinical specialists.
View Article and Find Full Text PDFIn children, gait and posture assessment provides a crucial marker for the early characterization, surveillance and treatment evaluation of early onset ataxia (EOA). For reliable data entry of studies targeting at gait and posture improvement, uniform quantitative biomarkers are necessary. Until now, the pediatric test construct of gait and posture scores of the Scale for Assessment and Rating of Ataxia sub-scale (SARA) is still unclear.
View Article and Find Full Text PDFAim: For reliable assessment of ataxia severity in children, the Childhood Ataxia and Cerebellar Group of the European Pediatric Neurology Society aimed to validate the Scale for Assessment and Rating of Ataxia (SARA) according to age.
Method: Twenty-two pediatric ataxia experts from 15 international institutions scored videotaped SARA performances in 156 typically developing children (4-16y: m/f=1; 12 children per year of age; including nine different nationalities). We determined age-dependency and reliability of pediatric SARA scores by a mixed model.
Early-Onset Ataxia (EOA) and Developmental Coordination Disorder (DCD) are two conditions that affect coordination in children. Phenotypic identification of impaired coordination plays an important role in their diagnosis. Gait is one of the tests included in rating scales that can be used to assess motor coordination.
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