Lipid Antigens: Revealing the Hidden Players in Adaptive Immune Responses.

Traditionally, research on the adaptive immune system has focused on protein antigens, but emerging evidence has underscored the essential role of lipid antigens in immune modulation. Lipid antigens are presented by CD1 molecules and activate invariant natural killer T (iNKT) cells and group 1 CD1-restricted T cells, whereby they impact immune responses to pathogens and tumors. Recent advances in mass spectrometry, imaging techniques, and lipidomics have revolutionized the identification and characterization of lipid antigens and enhanced our understanding of their structural diversity and functional significance.

The impact of noise-induced hearing loss on individual job performance: exploring the role of aggression and work-related quality of life.

Background: Noise-Induced Hearing Loss (NIHL) may have a significant effect on individual job performance (IJP). These effects may exert through aggression and work-related quality of life (WRQoL). Hence, the present study was conducted to investigate the modeling of the impact of NIHL on IJP by exploring the role of aggression and WRQoL.

The effect of COVID-19 anxiety on nurses' productivity determinants through perceived workload and individual job performance: A Bayesian mediation analysis.

This study aims to predict how COVID-19 anxiety affects productivity determinants by examining the role of perceived workload and individual job performance as mediators using Bayesian mediation analysis. To achieve the study's objectives, all nurses working at Imam Reza Hospital were recruited to participate. To gather data, all eligible and voluntary nurses were asked to complete questionnaires that included the Corona Disease Anxiety Scale (CDAS), Individual Job Performance Questionnaire (IJPQ), NASA Task Load Index (NASA-TLX), and Workforce Productivity Questionnaire.

Mercury levels in avian feathers from different trophic levels of eight families collected from the northern region of Iran.

Mercury levels were determined in feathers from 83 birds belonging to 18 species (eight families), all collected from the northern region of Iran. Mercury levels were evaluated in relation to taxonomic affiliation and feeding strategies. Mercury levels in the feathers were between 0.

Identification of differentially expressed genes in hepatocellular carcinoma and metastatic liver tumors by oligonucleotide expression profiling.

Background: The characterization of differentially expressed genes between cancerous and normal tissues is an important step in the understanding of tumorigenesis. Global gene expression profiling with microarrays has now offered a powerful tool to measure the changes of thousands of genes in any carcinoma tissues in an effort to identify these key disease-related genes. To compare the gene expression of a primary liver carcinoma, metastatic carcinoma to the liver, and normal liver, the authors analyzed tissue from six primary hepatocellular carcinomas (HCCs), five colorectal adenocarcinoma metastases to the liver, and eight normal livers.