[Diagnostic importance of the glucagon tolerance test in studying the islets of Langerhans apparatus of thyrotoxicosis patients].

Comparative studies of the glucagon-, OTTG- and BTTG tolerance test were performed in 50 patients, aged 25 to 50 years, glucagon being injected after intravenous and peroral glucose loading at hyperglycemic peak height. It was detected that a single intravenous glucagon injection provokes hyperglycemia mostly in healthy subjects than in patients with thyrotoxicosis during the first 15 to 30 minutes. Stimulating effect on insulin secretion was the same.

[Sensitivity to insulin in thyrotoxicosis].

Insulin and glucose-insulin sensitivity of peripheral tissues is studies in patients with thyrotoxicosis of different severity and duration. Three main types of the curves, characterizing exogenic insulin sensitivity, were detected. It was determined that a decrease in insulin sensitivity and insulin resistance prevailed in patients with disturbed glucose tolerance (the doubtful type of glycemic curve, latent diabetes).