Publications by authors named "T E Walshe"
Age-related macular degeneration (AMD) is one of the most common causes of visual impairment in the elderly, with a complex and still poorly understood etiology. Whole-genome association studies have discovered 34 genomic regions associated with AMD. However, the genes and cognate proteins that mediate the risk, are largely unknown.
View Article and Find Full Text PDFArticle Synopsis
- Biodiversity conservation decisions are challenging due to conflicting values, complex objectives, limited resources, and uncertainty, but decision science offers practical frameworks and tools to assist in these processes.
- The lack of training and confusion over terminology and tools has hindered the application of decision science, which does not have to be complicated or time-consuming if approached systematically.
- By breaking down decision analysis into clear steps and employing rapid-prototyping methods, decision-makers can effectively use decision-support tools and frameworks to navigate conservation challenges more efficiently.
Performance weighted aggregation of expert judgments, using calibration questions, has been advocated to improve pooled quantitative judgments for ecological questions. However, there is little discussion or practical advice in the ecological literature regarding the application, advantages or challenges of performance weighting. In this paper we (1) illustrate how the IDEA protocol with four-step question format can be extended to include performance weighted aggregation from the Classical Model, and (2) explore the extent to which this extension improves pooled judgments for a range of performance measures.
View Article and Find Full Text PDFScurvy is a disease that is rarely encountered in modern medicine. A condition that was classically associated with sailors, its incidence has decreased dramatically since the discovery of its association with vitamin C deficiency. We present the case of a 2-year-old boy, whose treatment for neuroblastoma was complicated by gastrointestinal disease, which necessitated enteral feeding.
View Article and Find Full Text PDFArticle Synopsis
- Natural resource management often relies on expert judgement, but these judgements are usually made using untested methods, which can be improved with structured approaches like the IDEA protocol.
- The IDEA protocol was tested with 76 participants estimating future events on the Great Barrier Reef, using a four-step process that involved investigation, discussion, estimation, and aggregation of opinions.
- Results showed that using the IDEA protocol not only enhanced the accuracy of judgements through group collaboration but also clarified communication and encouraged rigorous review, making it a valuable tool in scientific decision-making.