A Controlled Single-Centre Pilot Study to Evaluate the Effect of Prophylactic Surgery in Asymptomatic Degenerative Cervical Cord Compression.

Study DesignSingle-centre controlled pilot study.ObjectivesTo evaluate the effect of prophylactic surgery and to review the biases of a therapeutic trial in asymptomatic degenerative cervical cord compression (ADCC) patients.MethodsPatients with ADCC and at least 1 predictor of progression to symptomatic degenerative cervical cord myelopathy (DCM) were offered either prophylactic surgery or standard structured rehabilitation.

Representations of skin tone and sex in dermatology by generative artificial intelligence: a comparative study.

With generative artificial intelligence demonstrating potential in dermatologic education, assessment of skin tone diversity is imperative to ensure comprehensive patient care. Evaluating DALL-E3, Midjourney, and DreamStudio Beta, we generated five images for eight common dermatologic conditions designated by the American Academy of Dermatology. The Massey-Martin Skin Color Scale was used to evaluate the images, and interrater reliability was further assessed by a non-rater.

Cellular senescence predicts breast cancer risk from benign breast disease biopsy images.

Background: Each year, millions of women undergo breast biopsies. Of these, 80% are negative for malignancy but some may be at elevated risk of invasive breast cancer (IBC) due to the presence of benign breast disease (BBD). Cellular senescence plays a complex but poorly understood role in breast cancer development and the presence or absence of these cells may have prognostic value.

Hidradenitis Suppurativa Is Associated with an Increased Risk of Adverse Cardiac Events and All-Cause Mortality.

: Hidradenitis suppurativa (HS) has been previously associated with greater rates of major adverse cardiac events (MACEs) compared to the general population. This study aims to better elucidate the association between HS, MACEs, and other cardiovascular diseases. : We utilized TriNetX, a global database of electronic health records, to conduct a retrospective cohort study.

Magnetic resonance imaging measures of fat distribution and risk of cancer.

Background Excess adiposity has been associated with an increased risk of several types of cancer. The relationship of fat tissue distribution in the body with these outcomes is less well known. Using data from the UK Biobank imaging substudy, we evaluated the prospective relationship between MRI-derived measurements of adipose tissue distribution and the risk of the major site-specific cancers associated with obesity.