Stable ferrofluids of magnetite nanoparticles in hydrophobic ionic liquids.

Ferrofluids (FFs) of metal oxide nanoparticles in ionic liquids (ILs) are a potentially useful class of magnetic materials for many applications because of their properties related to temperature/pressure stability, hydrophobicity, viscosity and recyclability. In this work, the screening of several designer surfactants for their stabilizing capabilities has resulted in the synthesis of stable FFs of superparamagnetic 7 ± 2 nm magnetite (Fe3O4) nanoparticles in the hydrophobic IL 1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([C(R)MIM][NTf2]). The designed and synthesized 1-butyl-3-(10-carboxydecyl)-1H-imidazol-3-ium bromide (ILC10-COOH) surfactant that combines the same imidazole moiety as the IL with a long alkyl chain ensured compatibility with the IL and increased the steric repulsion between the magnetite nanoparticles sufficiently such that stable dispersions of up to 50 wt% magnetite were obtained according to stability tests in the presence of a magnetic field (0.

Pseudonormalisation of the T wave: old wine?: A fresh look at a 25-year-old observation.

A 74-year-old woman with documented coronary artery disease presented with symptoms of angina at rest. During these episodes of angina, the initial abnormal terminal negative T waves converted to normal positive T waves. In this article the significance of pseudonormalisation as a sign of ischaemia is reviewed.

Prehospital versus hospital fibrinolytic therapy using automated versus cardiologist electrocardiographic diagnosis of myocardial infarction: abortion of myocardial infarction and unjustified fibrinolytic therapy.

Background: This study investigated the incidence of abortion of myocardial infarction and of unjustified fibrinolysis by using automated versus cardiologist-assisted diagnosis of acute ST-elevation myocardial infarction. The results of prehospital diagnosis and treatment (2 cities in the Netherlands) were compared with those of inhospital treatment. Unjustified fibrinolysis must be differentiated from justified thrombolysis resulting in aborted myocardial infarction.

Prehospital thrombolysis with reteplase: the Nijmegen/Rotterdam study.

Objective: The objective of this observational study was to assess time from electrocardiogram diagnosis to treatment and time from pain onset to treatment with double bolus reteplase compared to current therapy with streptokinase or bolus anistreplase in 2 cities (Rotterdam and Nijmegen) in the Netherlands, where prehospital thrombolysis is an established way of treatment of acute myocardial infarction.

Methods: Prehospital thrombolysis is performed using electrocardiogram diagnosis by the ambulance service as well as bolus anistreplase for treatment in Nijmegen, and streptokinase infusion in Rotterdam. Reteplase or anistreplase/streptokinase was assigned open label to patients according to order of presentation on a 1-to-1 basis.

Abortion of acute ST segment elevation myocardial infarction after reperfusion: incidence, patients' characteristics, and prognosis.

Objectives: To study the incidence and patient characteristics of aborted myocardial infarction in both prehospital and in-hospital thrombolysis.

Design: Retrospective, controlled, observational study.

Setting: Two cities in the Netherlands, one with prehospital thrombolysis, one with in-hospital treatment.