Publications by authors named "T E Fox"
Objective: This study investigated methods of evaluating the bone fracture healing process using superb microvascular imaging (SMI; two modes color SMI [cSMI] and monochromeSMI [mSMI]), and shear wave elastography (SWE), relative to X-ray, dual-energy X-ray absorptiometry (DXA), and platelet endothelial cell adhesion molecule 1 (PECAM-1) also know as cluster of differentiation 31 (CD-31) staining in a rabbit model.
Methods: This IACUC-approved study involved eight rabbits that underwent a bilateral fibula osteotomy and were followed for 7 or 21 days (Groups 1 and 2 with 4 rabbits in each). Ultrasound examinations using cSMI, mSMI, and SWE were performed on Days 0, 4, 7, 14, and 21 post-surgery.
Article Synopsis
- Allogeneic haematopoietic stem cell transplantation (alloHSCT) shows high survival rates (90% overall survival) in adolescents and adults with severe inborn errors of immunity (IEI), as assessed in a study of 82 patients.
- The study found that pre-transplant immune dysregulation (measured by the IDDA v2.1 score) and the haematopoietic cell transplantation comorbidity index (HCT-CI) score significantly affected transplant outcomes, including overall survival and event-free survival.
- Notably, a portion of patients with a high IDDA v2.1 score and low HCT-CI score indicates that existing risk assessments may underestimate the risks of alloHSCT, highlighting