Topical nonsteroidal anti-inflammatory drugs for management of osteoarthritis pain: A consensus recommendation.

Osteoarthritis (OA) contributes to significant medical and socioeconomic burden in many populations. Its prevalence is expected to rise continuously owing to the combined effects of aging and increase in risk factors, including obesity, physical inactivity, and joint injuries. Pain is a hallmark presentation of OA.

Fibroblast-derived matrices-based human skin equivalent as an psoriatic model for drug testing.

Psoriasis is a chronic skin disease characterized by thickening and disorganization of the skin's protective barrier. Although current models replicate some aspects of the disease, development of therapeutic strategies have been hindered by absence of more relevant models. This study aimed to develop and characterize an psoriatic human skin equivalent (HSE) using human keratinocytes HaCat cell line grown on fibroblasts-derived matrices (FDM).

Comparing the cost, glycaemic control and medication adherence of utilizing patients' own medicines (POMs) versus usual dispensing among diabetic patients in an outpatient setting.

Background: Millions worth of unused drugs particularly those indicated for chronic diseases such as diabetes were returned and disposed leading to substantial wastage. Use of patients' own medications (POMs) in the inpatient setting has reduced wastage and saved cost. The impact of utilizing POMs in the outpatient setting has hitherto not been determined.

Spontaneous cutaneous extrusion of a parotid gland sialolith.

Parotid gland sialolithiasis is an uncommon condition that can cause pain and recurrent infection in affected patients. Migration of a stone through a fistula is a rare but possible complication of untreated sialolithiasis. We present a case of parotid gland sialolithiasis in a 63-year-old woman with recurrent episodes of parotitis and facial pain, which resolved through spontaneous extrusion of the stone (11 mm) through a cutaneous fistula while awaiting surgery.