[The vascular wall in postmenopausal women with hypothyroidism and hypertension].

Aim: To study a relationship between thyroid function and the stiffness of great arteries in postmenopausal women with arterial hypertension (AH).

Subjects And Methods: The trial enrolled 76 postmenopausal patients with clinical hypothyroidism (CHT) (n = 24) or subclinical hypothyroidism (SCHT) (n = 52) and AH; a control group consisted of 40 postmenopausal women with euthyroidism. Body mass index (BMI), waist and hip circumferences, blood pressure (BP), thyroid-stimulating hormone (TSH), free thyroxine, free triiodothyronine, total cholesterol, triglycerides were determines; volumetric sphygmography was performed.

[Anxiety-depressive disorders in patients with type 2 diabetes mellitus complicated with acute coronary syndrome].

Psychological status of 140 patients with type 2 diabetes mellitus (DM) and acute coronary syndrome (ACS) was studied on the 12-th day after the moment of admission to the cardioreanimation department and in 6 months after discharge from hospital. Spielberger questionnaire was used for assessment of level of personal and reactive anxiety, Beck scale -- for estimation of level of depression, and Holmes - Ray scale -- for calculation of total number of stressful events. Average level of anxiety in acute period of ACS corresponded to high level of anxiety disorders (reactive anxiety score 47.

[The role of inflammation factors in development of acute coronary syndrome in patients with type 2 diabetes mellitus and impaired glucose tolerance].

Aim: To study the levels of inflammatory markers in acute coronary syndrome (ACS) and 6 months after its regression in patients with diabetes mellitus (DM) type 2; to evaluate effects of anxiodepressive disorders on inflammatory markers.

Material And Methods: The levels of high-sensitive C-reactive protein (hsCRP), interleukin-6 (IL-6), interleukin-18 (IL-18), monocyte-chemmoattractant-protein-1 (MCP-1) and soluble vascular cell adhesion molecules (sVCAM) were measured in blood samples, severity of depressive symptoms and the level of glycated haemoglobin (HbA1c) were assessed in 58 patients with type 2 DM during ACS and in 54 patients 6 months after ACS regression.

Results: The levels of hsCRP and IL-18 correlate significantly with severity of myocardial lesion in ACS (p < 0.