A closed-loop negative feedback model for the pancreas: A new paradigm and pathway to a cure.

Background And Aims: To develop a model that describes how the pancreas functions, how the rate of synthesis of digestive enzymes is regulated, and finally what puts the pancreas to rest between meals.

Methods: We applied the principals of control theory to previously published canine data to develop a model for how the canine pancreas functions. Using this model, we then describe the steps needed to apply this model to the human pancreas.

AN ALGORITHM TO DETERMINE THE NANODOSIMETRIC IMPACT OF GOLD NANOPARTICLES ON CELL MODELS.

High-Z nanomaterials, e.g. gold nanoparticles (GNPs), are being investigated worldwide for potential application in radiation imaging and therapy.

Recurrent Surgical Site Infections in the Spine After Treatment With the Vacuum-assisted Closure (VAC) System.

Study Design: This study retrospectively reviewed recurrences of surgical site infections (SSI) in spinal patients treated with vacuum-assisted closure (VAC) technology.

Objective: Identify patient and treatment factors associated with recurrence of SSI after VAC treatment.

Summary Of Background Data: Patients treated with VAC can achieve healing of deep spine wound infections; however, some patients develop a recurrent infection.

Effect of the factor Xa inhibitor rivaroxaban on arterial thrombosis in wild-type and apolipoprotein E-deficient mice.

Rivaroxaban is a potent and specific direct inhibitor of coagulation factor Xa. Recent studies have highlighted its effectiveness in the prevention of venous thrombosis and embolic stroke due to atrial fibrillation. To evaluate the antithrombotic effects of rivaroxaban in an in vivo model of arterial thrombosis, photochemical vascular injury was induced in wild-type mice by intravenous rose bengal (50 mg/kg body weight [BW]) followed by illumination of the left common carotid artery using a 543 nm helium-neon laser beam.

Discussion of laser-assisted liposuction.

Unlabelled: There has been a significant advancement in the use of lasers for body contouring over the past several years. This article will review the recent past and discuss the future of this trend.

Introduction: There is much confusion over the definition of procedures using lasers for lipolysis and liposuction.