Dental abnormalities observed in the oculo-facio-cardio-dental (OFCD) syndrome present in two Czech families bearing novel de novo BCOR pathogenic variants.

Background: The oculo-facio-cardio-dental syndrome (OFCD) is an ultra-rare multiple congenital anomaly. This report describes clinical findings emphasising dental phenotype in five, molecularly confirmed, female cases from two Czech families.

Case Presentation: Dental examinations were carried out.

Comparison of the reverse scan technique with an intraoral scanner and the traditional impression technique.

Statement Of Problem: Intraoral scanners have many advantages but have limited applicability for extensive tooth-supported or implant-supported prostheses because of merging errors.

Purpose: The purpose of this study was to compare the reverse scan technique (RST) with an intraoral scanner using the traditional impression technique both in vitro and in vivo.

Material And Methods: A participant was scanned 10 times with an intraoral scanner.

Reverse scan technique: A verification method for the implant position in intraoral scans.

This article describes a fully digital method of verifying and increasing the accuracy of the position of implants in extensive prosthetic restorations. This cost-effective, timesaving, and versatile procedure uses a laboratory scanner, a scannable implant analog, and a printed interim implant-supported prosthesis to refine the virtual definitive cast.

: Next-generation sequencing sheds light on Witkop's classification.

Amelogenesis imperfecta (AI) is a heterogeneous group of genetic rare diseases disrupting enamel development (Smith et al., Front Physiol, 2017a, 8, 333). The clinical enamel phenotypes can be described as hypoplastic, hypomineralized or hypomature and serve as a basis, together with the mode of inheritance, to Witkop's classification (Witkop, J Oral Pathol, 1988, 17, 547-553).