Publications by authors named "T Dondaine"

Article Synopsis
  • Anxiety is common after ischemic stroke, with a prevalence of 35%, and more pronounced in females.
  • The study analyzed data from 584 patients, finding that those with post-stroke anxiety often had lower education levels, more severe strokes, and higher rates of depression and cognitive impairment.
  • The findings highlight the connection between post-stroke anxiety and cognitive issues, suggesting that individuals with cognitive impairments are more likely to experience anxiety after a stroke.
View Article and Find Full Text PDF

Objectives: The few voxel-wise lesion-symptom mapping (VLSM) studies aimed at identifying the anatomy of executive function are limited by the absence of a model and by small populations. Using Trail Making Test (TMT) and verbal fluency and a model of their architectures, our objective was to identify the key structures underlying two major executive processes, set-shifting and strategic word search.

Methods: We applied a validated VLSM analysis to harmonized cognitive and imaging data from 2009 ischemic stroke patients as a part of the Meta VCI Map consortium.

View Article and Find Full Text PDF

Background: The origin of pre-existing cognitive impairment in stroke patients remains controversial, with a vascular or a degenerative hypothesis.

Objective: To determine whether endothelial dysfunction is associated with pre-existing cognitive problems, lesion load and biological anomalies in stroke patients.

Methods: Patients originated from the prospective STROKDEM study.

View Article and Find Full Text PDF

The misuse of benzodiazepines and opioid medications is frequent in students. To improve our understanding of this behavior, we aimed to identify factors associated with separate and concomitant use of these substances. Anonymous self-reported questionnaires were e-mailed to students enrolled at a French university between March and July 2021, covering: sociodemographic characteristics, academics, psychoactive substance use, ADHD symptomatology (adulthood and childhood), and psychiatric/psychological or addiction follow-up.

View Article and Find Full Text PDF

Background: Post-stroke cognitive impairment (PSCI) occurs in up to 50% of stroke survivors. Presence of pre-existing vascular brain injury, in particular the extent of white matter hyperintensities (WMH), is associated with worse cognitive outcome after stroke, but the role of WMH location in this association is unclear.

Aims: We determined if WMH in strategic white matter tracts explain cognitive performance after stroke.

View Article and Find Full Text PDF