Publications by authors named "T Djumhana Atmakusuma"
: Indonesia, as a developing country, has limited data on the factors associated with 30-day mortality in COVID-19 patients in Indonesia. As a matter of fact, study analyzing factors associated with 30-day mortality of COVID-19 infection in Indonesia has never been conducted. This study aims to fill this gap in the literature by conducting a large-scale analysis of factors associated with 30-day mortality in COVID-19 patients in Indonesia.
View Article and Find Full Text PDFIn recent years, considerable progress has been made in the standard treatment for chronic lymphocytic leukaemia (CLL) due to the availability of new potent drugs. However, the majority of data on CLL were derived from Western populations, with limited studies and guidelines on the management of CLL from an Asian population perspective. This consensus guideline aims to understand treatment challenges and suggest appropriate management approaches for CLL in the Asian population and other countries with a similar socio-economic profile.
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- The study investigates the role of Epstein-Barr Virus (EBV) oncoproteins (specifically EBNA1 and LMP1) and immune markers (CD4, CD8, FOXP3) in patients with nasopharyngeal cancer to understand their association with tumor progression.
- 23 nasopharyngeal cancer samples were analyzed, revealing a moderate correlation between LMP1 and tumor volume, a strong correlation between CD8 levels and tumor volume, and a moderate correlation between FOXP3 and tumor volume, while no correlation was found for neck nodal metastases.
- The findings suggest that larger primary tumors were linked to increased CD8 markers, indicating a possible dysfunction in CD8 T cells,
Indonesia is located along the 'Thalassemia Belt' and a hotspot for hemoglobinopathies. Around 3.0-10.
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- People with transfusion-dependent thalassemia are at higher risk of COVID-19 due to internal and external factors, but anecdotal evidence suggests they may have lower infection rates than the general population.
- A study conducted in Indonesia from May 2020 to August 2021 found that only 0.64% of thalassemia patients contracted COVID-19 compared to 0.87% in the general population, indicating potential protective factors for thalassemia patients.
- The findings suggest that countries with high thalassemia prevalence, like Indonesia, experience lower COVID-19 incidences, possibly due to unique biological mechanisms associated with thalassemia.