Publications by authors named "T Dewaele"

Article Synopsis
  • Achieving first-pass recanalization (FPR) during thrombectomy is crucial for better clinical outcomes in acute ischemic stroke patients, making it important to understand the factors that cause FPR failures.
  • This study examined the relationship between thrombus composition and the success rates of FPR by analyzing thrombi from 267 stroke patients.
  • Results showed that thrombi leading to successful FPR had more red blood cells and less fibrin and extracellular DNA, suggesting that certain thrombus characteristics can influence the likelihood of achieving FPR.
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Background: Mechanical removal of a thrombus by thrombectomy can be quite challenging. For reasons that are not fully understood, some thrombi require multiple passes to achieve successful recanalization, whereas other thrombi are efficiently removed in a single pass. Since first pass success is associated with better clinical outcome, it is important to better understand the nature of thrombectomy resistant thrombi.

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Background: With the increasing age of acute stroke patients being admitted to hospitals, more data are needed on indications, complications and outcome of endovascular treatment (EVT) in the very elderly.

Methods: Retrospective observational study with data collection from Belgian, Swiss, Canadian comprehensive stroke centers and Swedish EVT National database. All patients with acute ischemic stroke were eligible if aged older than or ≥90 years and treated with EVT ± pretreatment with intravenous thrombolysis (IVT).

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Ischemic stroke is caused by a thromboembolic occlusion of cerebral arteries. Treatment is focused on fast and efficient removal of the occluding thrombus, either intravenous thrombolysis or endovascular thrombectomy. Recanalization, however, is not always successful and factors contributing to failure are not completely understood.

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Purpose: The evaluation of clinical image quality (IQ) is important to optimize CT protocols and to keep patient doses as low as reasonably achievable. Considering the significant amount of effort needed for human observer studies, automatic IQ tools are a promising alternative. The purpose of this study was to evaluate automatic IQ assessment in chest CT using Thiel embalmed cadavers.

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