Publications by authors named "T Delory"
Brentuximab vedotin (BV)-bendamustine (90 or 120 mg/m2 day 1 and 2) every 28 days is an effective treatment for relapsed/refractory Hodgkin lymphoma (R/R HL) but associated to high toxicity especially for elderly patients. We conducted in St Louis Hospital, Paris, between 2015 and 2021 a retrospective single-center analysis of 44 patients with R/R HL treated with one-day BV-bendamustine (120 mg/m2) every 21 days. Sixteen percent of patients were ≥ 60 years old (yo).
View Article and Find Full Text PDFIntroduction: Sleep and mood disorders are common in hemodialysis, but the effect of light therapy remains unknown in this population.
Methods: We conducted a randomized, controlled, open-label pilot trial comparing two group of either 30 minutes of light therapy three times a week, or no exposure. The primary endpoint was change in sleep quality (PSQI) after five weeks of light therapy, with change in mood (DASS-21) as a secondary endpoint.
We show the value of real-time data generated by a computerized decision support system in primary care in strengthening pneumonia surveillance. The system showed a 66% (95% CI 64%-67%) increase in community-acquired pneumonia from 2018 to 2023 for the population of France, 1 month before a national alert was issued.
View Article and Find Full Text PDFArticle Synopsis
- A study analyzed lung cancer cases in France during the COVID-19 pandemic by comparing 2020-2021 data with pre-pandemic years (2013-2019), focusing on diagnosis and mortality rates.
- Findings revealed a 12% decrease in newly diagnosed lung cancer cases during the first wave of the pandemic, with a continued improvement in survival rates over time, even during the pandemic.
- The decrease in lung cancer incidences could be linked to undiagnosed patients who died due to COVID-19 or challenges in accessing healthcare, leading to excess mortality during this period.
Background: Suboptimal use of antimicrobials is a driver of antimicrobial resistance in West Africa. Clinical decision support systems (CDSSs) can facilitate access to updated and reliable recommendations.
Objective: This study aimed to assess contextual factors that could facilitate the implementation of a CDSS for antimicrobial prescribing in West Africa and Central Africa and to identify tailored implementation strategies.