Publications by authors named "T Delnoij"
Long-term cognitive impairment is common in cardiac arrest survivors. Screening to identify patients at risk is recommended. Functional magnetic resonance brain imaging (fMRI) holds potential to contribute to prediction of cognitive outcomes.
View Article and Find Full Text PDFMonitoring of myocardial injury by serial measurements of QRS area and T area: The MaastrICCht cohort.
Ann Noninvasive Electrocardiol
September 2024
Background: Manually derived electrocardiographic (ECG) parameters were not associated with mortality in mechanically ventilated COVID-19 patients in earlier studies, while increased high-sensitivity cardiac troponin-T (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) were. To provide evidence for vectorcardiography (VCG) measures as potential cardiac monitoring tool, we investigated VCG trajectories during critical illness.
Methods: All mechanically ventilated COVID-19 patients were included in the Maastricht Intensive Care Covid Cohort between March 2020 and October 2021.
Article Synopsis
- In out-of-hospital cardiac arrest (OHCA) cases without ST-elevation, researchers investigated the usefulness of troponin-T (cTnT) levels in predicting the risk of acute coronary syndrome and patient survival.
- The study analyzed data from 352 patients, revealing that higher cTnT values were independent predictors for 90-day mortality and the presence of acute unstable lesions and thrombotic occlusions.
- However, cTnT levels did not show a significant correlation with left ventricular function, highlighting its role primarily in assessing mortality risk and acute coronary issues in these patients.
Article Synopsis
- A Bayesian meta-analysis was conducted to evaluate the effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) compared to conventional CPR in patients who had a cardiac arrest outside of the hospital, focusing on neurological outcomes after 6 months.
- The analysis included data from three randomized trials, with ECPR involving 209 patients and conventional CPR involving 211 patients, and aimed to clarify the probability of clinically significant treatment effects rather than relying solely on p-values.
- Results showed that ECPR had a median relative risk of 1.47 for neurologically favorable survival in all rhythms and 1.54 for patients with shockable rhythms, indicating a potential benefit, but with wide credible intervals suggesting uncertainty
Article Synopsis
- A study examined health-related quality of life (HRQoL) in patients who survived out-of-hospital cardiac arrest (OHCA) treated with either extracorporeal cardiopulmonary resuscitation (ECPR) or conventional CPR (CCPR) during the first year post-incident.
- Out of 134 enrolled patients, only 20% survived to hospital discharge, with HRQoL assessed for 25 survivors using the EQ-5D-5L questionnaire, revealing 68% had good HRQoL after one year.
- Although there was no significant statistical difference in HRQoL scores between ECPR and CCPR groups, results suggested that ECPR survivors experienced numerically better outcomes,