Publications by authors named "T Davis"
p53 is a potent transcription factor that is crucial in regulating cellular responses to stress. Mutations in the gene are found in >50% of human cancers, predominantly occurring in the DNA-binding domain (amino acids 94-292). The Y220C mutation accounts for 1.
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- Early identification of hereditary cancer predisposition in adolescents and young adults is crucial for targeted cancer prevention and improving survival rates, but this age group faces unique healthcare transition challenges.
- The study aimed to gather expert insights on creating a transition clinic for this demographic, using qualitative methods inspired by human-centered design and implementation science.
- Key findings emphasized the importance of relationship building, care coordination, education, effective communication among providers, and establishing a sustainable clinic model to enhance program implementation.
This study aims to enhance sustainable disease management in black gram by identifying varieties resistant to Mungbean Yellow Mosaic India Virus (MYMIV). We screened sixteen black gram genotypes, assessing physiological, biochemical and enzymatic basis. Results revealed a range of resistance levels, with PANT URD-19 showing the highest resistance (PDI 0.
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- Doxycycline postexposure prophylaxis (doxyPEP) effectively reduces the incidence of bacterial sexually transmitted infections (STIs) in those assigned male at birth, although practical data is limited.
- This study analyzed electronic health records of HIV PrEP users from Kaiser Permanente Northern California to assess the uptake of doxyPEP and its impact on STI rates before and after its initiation.
- Out of 11,551 HIV PrEP users, 19.5% received doxyPEP, with a notable percentage having an STI prior; findings suggest changes in STI positivity rates among those who started doxyPEP versus those who did not.
BACKGROUND Although hypomagnesemia is common in type 2 diabetes, clinical presentations with severe hypomagnesemia are rare. A number of oral blood glucose-lowering medications can reduce serum magnesium concentrations, and several severe cases have been reported in the presence of marked glucagon-like peptide-1 receptor agonist (GLP-1RA)-associated gastrointestinal adverse effects. In the present case, an acute presentation with severe hypomagnesemia was likely due to polypharmacy including semaglutide, albeit with a delayed relationship to discontinuation of this GLP-1RA, due to nausea and vomiting.
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