Publications by authors named "T Daix"
Background: Ventilator-associated pneumonia (VAP) is the main healthcare-associated infection in intensive care units with Staphylococcus aureus as the first pathogen in early VAP.
Aim: To compare, using whole-genome sequencing (WGS), consecutive S. aureus isolates from lower respiratory samples of mechanically ventilated patients for identification of potential cross-transmissions; and to determine a potential link between S.
Article Synopsis
- - Ventilator-associated pneumonia (VAP) is common in cardiac arrest patients, but diagnosing it post-arrest is difficult, leading to debate over the effectiveness of biomarkers like C-reactive protein (CRP) and procalcitonin (PCT) for this purpose.
- - The study analyzed the role of various biomarkers in diagnosing and predicting VAP within 48 hours following cardiac arrest and therapeutic hypothermia, using a randomized clinical trial as a foundation.
- - Results showed that VAP patients had distinct clinical features and higher biomarker levels indicating VAP; CRP was notably associated with VAP, demonstrating an area under the curve (AUC) greater than 0.70 in analyses.
Background: A notable increase in severe cases of COVID-19, with significant hospitalizations due to the emergence and spread of JN.1 was observed worldwide in late 2023 and early 2024. However, no clinical data are available regarding critically-ill JN.
View Article and Find Full Text PDFSeptic patients with worst clinical prognosis have increased circulating immature granulocytes (IG), displaying limited phagocytosis and reactive oxygen species (ROS) production. Here, we developed an model of incubation of human granulocytes, from septic patients or healthy donors, with . We showed that the ROS production in Sepsis-IG is lower due to decreased activation and protein expression of the NADPH oxidase complex.
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