[Effects of 1-hydroxyethylidene-1,1-bisphosphonate (HEBP) on the formation of dental hard tissue of mouse molar tooth germs in organ culture system].

In the developing tooth, 1-hydroxyethylidene-1,1-bisphosphonate (HEBP) causes hypoplasia and hypomineralization of enamel and dentine. The present study was undertaken to clarify the effects of HEBP on the formation of dental tissues of tooth germs in an organ culture system. Mandibular first molars from 17.