Assessment of early age healthy Georgian children's physical, motor and psychosocial development by BINS (Bayley Infant Neurodevelopmental Screener).

Physical, motor and psychosocial development has been studied in healthy Georgian infants and early age children who were born without biological risks. Neurological, receptive, expressive and cognitive functions were assessed by BINS (Bayley's Infant's Neurodevelopmental screener). Comparing to the norm given by BINS, analyses of variances shows a significant difference of median sum indicators in all age groups.

[Rationale for using kinin system inhibitors in patients with acute ischemia and infarction of the myocardium during the prehospital phase].

The paper discusses if it is advisable to use kallikrein-kinin system inhibitors earlier. A total of 122 patients with acute ischemia and infarction of the myocardium were studied. Contrykal and heparin infused in the prehospital period, followed by hospital treatment are optimal to prevent vascular wall lesions, maximally retain retrograde blood flow, and substantially reduce the size of myocardial infarction.

[Effect of inosine after early infusion of contrykal and heparin in various hemodynamic types of acute myocardial ischemia].

In 79 experiments with a canine model of acute 2-hour myocardial ischemia, a positive affect of inosine was found on parameters of cardiac bioelectrical activity, contractile and hemodynamic functions in normal and hypodynamic circulation. In excessive myocardial hyperfunction, inosine infusion led to aggravation of ischemic signs in the ischemic lesion zone and only to its modest decrease in the adjacent and intact segments of the myocardium. During pre-infusion of contrykal and heparin followed by inosine administration, there was a considerable decrease in ischemia in all myocardial areas, as evidenced by ECG and electrograms, no matter what the hemodynamic type of acute myocardial ischemia.