Publications by authors named "T D Plant"

Article Synopsis
  • The study focuses on short- and long-term antibody responses to pneumococcal vaccines in HIV-infected adults, comparing two types of vaccines: Pneumovax-23 (PPV) and Prevenar-13 (PCV).
  • A subgroup of 152 participants from a larger study had their antibody levels measured before and after vaccination, with ongoing assessments for four years. Results indicated that those vaccinated with PCV had a higher likelihood of achieving the World Health Organization's antibody threshold than those who received PPV.
  • Specifically, 54% of PCV recipients reached the target after one dose compared to 33% with PPV, and this advantage continued with booster doses, showing better cumulative rates
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Objectives: Lung cancer is the leading cause of cancer death in the UK. Prehabilitation aims to maximise patient fitness and minimise the negative impact of anticancer treatment. What constitutes prehabilitation before non-surgical anticancer treatment is not well established.

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There is a need to close the gap between knowledge and action in health care. Effective care requires a convenient and reliable distribution process. As global internet and mobile communication increase capacity, innovative approaches to digital health education platforms and care delivery are feasible.

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Article Synopsis
  • The study investigates the presence of salivary antibodies against SARS-CoV-2 in healthcare workers, both after infection and vaccination, revealing that while serum antibodies are common, salivary antibodies are less prevalent and often non-neutralising.
  • Serum samples showed a high prevalence of IgG antibodies after vaccination, but only a fraction also showed salivary antibodies, indicating a disconnect between systemic and mucosal immune responses.
  • The findings emphasize the necessity for mucosal vaccines to improve oral and nasopharyngeal immunity, as salivary antibodies alone cannot reliably reflect overall antibody response from serum measurements.
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