Publications by authors named "T D Nykula"

Background: The pathogenesis of hepatic encephalopathy (HE) is only partially understood. Beside ammonia accumulation in brain, a proinflammatory component has been suggested as precipitating event.

Objectives: To evaluate the role of cytokines in cirrhosis for development of HE.

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The data on the positive experience with hepatic encephalopathy in patients with cirrhosis liver L-ornithine-L-aspartate (drug larnamyn), the effectiveness of which is provided by its components (amino acids, ornithine and aspartate) which improve metabolism, ammonia detoxification mechanism, production of energy in the Krebs cycle, promote restoration of the cell membrane, and carried out anti-inflammatory and detoxicative effect.

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Glucocorticoids have high anti-inflammatory activity useful in the treatment of acute glomerulonephritis, nephrotic syndrome. The main course of treatment is based on results of morphological verification of the diagnosis.

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In summary, to come to objective conclusions as proven treatment that achieved by improvement schemes. Detected somewhat smaller difference in the degree of risk in the treatment of existing and improved schemes ulcer and neasotsiyovanoyi it when the underlying disease complicated by chronic inflammation, in our opinion, due to greater perfection, adapted first for this category of patients, among other options.

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In the article the results of estimation of basic indexes of cellular and humoral link of immune system and cytokine status are resulted for patients with essential hypertension in combination with osteoarthritis and also influences of complex therapy of essential hypertension and osteoarthritis on these indexes are resulted.

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