Sex-Based Differences in Endovascular Thrombectomy Outcomes for Large Ischemic Stroke: A SELECT2 Subanalysis.

Background: Several social and biological factors are shown to differentially affect stroke outcomes between men and women. We evaluated whether clinical outcomes and endovascular thrombectomy (EVT) treatment effects differed between the sexes in patients presenting with large ischemic stroke.

Methods: The SELECT2 trial (A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke) was a randomized controlled trial assessing the efficacy and safety of EVT in patients with large strokes across the United States, Canada, Europe, Australia, and New Zealand between October 2019 and September 2022.

Expressing red fluorescent protein on the surface of using C-terminal domain of autotransporters.

The Type V secretion system, or "autotransporter", is a secretion system that enables bacteria to directly export proteins from the cell interior to the extracellular membrane. mCherry is a second-generation monomeric red fluorescent protein that has an improvement in photostability compared to the first generation of RFP. In this research, we conducted the fusion of the mRFP into the C-terminal domain of EhaA - the translocation domain of the autotransporter protein transport system - to investigate the expression of mRFP on the surface of a model organism commonly utilized in recombinant protein research.

Neonatal sepsis in Vietnam: Bacterial profiles and antibiotic susceptibility in a tertiary care setting.

Background: Neonatal sepsis is a leading cause of newborn mortality, particularly in low and middle-income countries. This study examines the bacterial etiologies and antibiotic resistance patterns of neonatal sepsis in a tertiary hospital in Vietnam.

Methods: A prospective cross-sectional study was conducted at National Children's Hospital, Hanoi, Vietnam from January 2021 to December 2022.

Foot and Ankle Reconstruction Using Retrograde Lateral Supramalleolar Flap.

 Treatment of soft-tissue defects in the foot and ankle is a challenge. The use of a retrograde lateral supramalleolar flap is a promising technique for reconstruction. This study aims to assess the efficacy and outcomes of the technique.