[Late-replicating regions in salivary gland polytene chromosomes of Drosophila melanogaster].

About 240 specific regions that are replicated at the very end of the S-phase have been identified in D. melanogaster polytene chromosomes. These regions have a repressive chromatine state, low gene density, long intergenic distances and are enriched in tissue specific genes.

18 wheeler regulates apical constriction of salivary gland cells via the Rho-GTPase-signaling pathway.

Rho GTPase and its upstream activator, guanine nucleotide exchange factor 2 (RhoGEF2), have emerged as key regulators of actin rearrangements during epithelial folding and invagination (Nikolaidou, K.K., Barrett, K.

NETRIN and SLIT guide salivary gland migration.

Directed migration is pivotal for the proper placement and function of nearly all organs. The majority of known guidance molecules involved in directed migration have been identified from studies of migrating axons during nervous system development. Here, we show that at least two of these axon guidance molecules, NETRIN and SLIT, act through their canonical receptors, to guide Drosophila embryonic salivary glands.