Analysis of nuclear receptor expression in head and neck cancer.

Objective: Studies of squamous cell carcinoma of the head and neck (HNSCC) have demonstrated the importance of nuclear receptors and their associated coregulators in the development and treatment of HNSCC. We sought to characterize members of the nuclear receptor super family through interrogation of RNA-Seq and microarray data.

Materials And Methods: TCGA RNA-Seq data within the cBioportal platform comparing HNSCC samples (n = 515 patients with RNA-Seq data) to normal tissue (n = 82 patients) was interrogated for significant differences in nuclear receptor expression.

"Hanging on by a Thread": The Lived Experience of Parents of Children with Medical Complexity.

Background: Families with children with medical complexity endure high levels of chronic and toxic stress, impacting the overall health and wellbeing of all family members and the system as a whole. The purpose of this study was to examine the lived experiences of parents/caregivers with children with medical complexity.

Methods: The lived experiences of 15 parents of children with complex medical needs were explored using focus group discussions.

A Hospital-Based Infant Safe Sleep Intervention and Safe Sleep Practices Among Young Women: A Prospective Longitudinal Study.

Introduction: The rates of sudden unexpected infant death (SUID) are still high in the U.S. The longitudinal effects of SUID preventive education on infant safe sleep practices are less known.

Pneumonia and meningitis in a Beagle Dog caused by .

A 5-year-old female Beagle Dog was euthanized following ten days of inappetence, lethargy, and pain in the left cervical region that was not responsive to steroids or antibiotics. At necropsy, there were multiple soft dark red to tan nodules throughout all lung lobes, abundant purulent subdural exudate over the right temporal lobe of the brain, and minimally enlarged submandibular and tracheobronchial lymph nodes. Impression smear of the subdural pus and histologic section of the lung and meninges demonstrated small aggregates of rod-shaped to filamentous bacteria often surrounded by Splendori-Hoeppli material.

Psychological Attachment Orientation and Long-Term Posttraumatic Stress Symptoms Among Family Members of ICU Patients.

Unlabelled: To determine the degree to which an ICU patient's family member having an "anxious" psychologic attachment orientation is a risk factor for developing long-term posttraumatic stress disorder (PTSD) symptoms following patient ICU discharge or death.

Design: Prospective cohort study.

Setting: Single academic neuroscience ICU from November 2017 to September 2020.