Perceptions of Machine Learning among Therapists Practicing Applied Behavior Analysis: A National Survey.

Unlabelled: Collecting data and logging behaviors of clients who have autism spectrum disorder (ASD) during applied behavior analysis (ABA) therapy sessions can be challenging in real time, especially when the behaviors require a rapid response, like self-injury or aggression. Little information is available about the automation of data collection in ABA therapy, such as through machine learning (ML). Our survey of ABA therapists nationally revealed mixed levels of familiarity with ML and generally neutral responses to statements endorsing the benefits of ML.

Comparative analysis of the fit quality of monolithic zirconia veneers produced through traditional and digital workflows using silicone replica technique: an in vitro study.

Background: The success of a restoration largely depends on the quality of its fit. This study aimed to investigate the fit quality of monolithic zirconia veneers (MZVs) produced through traditional and digital workflows.

Methods: A typodont maxillary right central incisor was prepared.

A specific gene expression program underlies antigen archiving by lymphatic endothelial cells in mammalian lymph nodes.

Lymph node (LN) lymphatic endothelial cells (LEC) actively acquire and archive foreign antigens. Here, we address questions of how LECs achieve durable antigen archiving and whether LECs with high levels of antigen express unique transcriptional programs. We used single cell sequencing in dissociated LN tissue and spatial transcriptomics to quantify antigen levels in LEC subsets and dendritic cell populations at multiple time points after immunization and determined that ceiling and floor LECs archive antigen for the longest duration.

New Shikimic Acid Derivatives From the Marine-Derived Actinomycete Streptomyces sp. G666 and Their Antimicrobial Activities.

Analysis of an antimicrobial extract from the agar-based culture of the marine-derived actinomycete Streptomyces sp. G666 led to the isolation of three new shikimic acid derivatives, streptomine A-C (1-3), along with five known compounds (4-8). Their structures were established by their spectral data analyses, including MS and NMR.