The authors compared cytotoxicity of magnetite (Fe3O4) particles in nanometric ranges (10 nm and 50 nm) and micrometer range (1 microm), analyzing changes in cellular subunits of bronchoalveolar lavage in 24 hours after intratracheal application of the particles. Findings are that the nanoparticles are more biologically aggressive than the micrometric particles, but induce more active and effective defensive reaction of alveolar fagocytosis.
View Article and Find Full Text PDFThe authors summarize theoretical principles of increasing human resistence to toxic effects of inorganic compounds polluting occupational environment and habitat, exemplify practical use of this prophylactic trend.
View Article and Find Full Text PDFThe paper presents experimental and theoretical rationales for some methods and means of biological prevention of the toxic effects of a number of heavy metals (lead, chromium, arsenic, cadmium) that pollute the environment. Subchronic experiments were made on laboratory animals exposed to the above substances in combination with various biological agents (sodium glutaminate, the adaptogen saparal, pectin-containing enterosorbent, calcium, the multivitamin-multimineral preparation Pikovit, etc.).
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