Publications by authors named "T D Cecil"
Introduction: Intraabdominal collections (IACs) are common following cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). Inflammatory biomarkers and nutritional index (NI) may predict IACs. Management of IACs with image guided percutaneous drainage (IGPD) is an alternative to laparotomy.
View Article and Find Full Text PDFTargeted Genetic Sequencing Analysis of 223 Cases of Pseudomyxoma Peritonei Treated by Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Shows Survival Related to GNAS and KRAS Status.
Cancer Med
October 2024
Background And Aim: Pseudomyxoma peritonei (PMP) is an unusual condition with unique behaviour caused by a mucinous neoplasm, usually arising from the appendix. The aim of this study was to evaluate the prevalence of genomic alterations in clinical specimens of PMP using a targeted assay and correlate the findings with clinical, pathological and outcome data. Sequencing data from 223 patients were analysed.
View Article and Find Full Text PDFArticle Synopsis
- Scientists studied the kinematic Sunyaev-Zel'dovich (kSZ) effect using data from two telescopes, the South Pole Telescope and Herschel-SPIRE, covering a large area in the sky.
- They found a strong signal indicating that there is a trispectrum, which is a kind of pattern in the data, but it had contributions from other sources too, like cosmic microwave background lensing and foregrounds.
- By analyzing the data, they couldn't find just the kSZ signal alone, but they set limits on how long the reionization period lasted in the early universe, which helps us understand its history better.
Background: The presence at diagnosis, or development of, colorectal peritoneal metastases (CPM) is common in colorectal cancer. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) show promising results in selected patients with CPM. The current study aimed to describe oncologic outcomes of patients with CPM, focusing on recurrence patterns and risk factors for adverse events.
View Article and Find Full Text PDFBackground: The role of gastrectomy to achieve complete cytoreduction (CCR) for pseudomyxoma peritonei (PMP) is controversial due to uncertain risk/benefit ratio. The outcomes of patients who gastrectomy over a twenty-year period in a high-volume unit are reported.
Methods: All patients requiring gastrectomy to achieve CCR for appendiceal PMP between 2000 and 2020 were reviewed.