Publications by authors named "T D Buitenkamp"

Article Synopsis
  • Some kids who had a type of blood cancer called acute lymphoblastic leukemia (ALL) might get another type of cancer called non-Hodgkin lymphoma (NHL) after their treatment.
  • In a study of 85 kids with NHL after ALL, most cases happened during or soon after their main treatment.
  • Many of these kids had weakened immune systems, which is important to know for better and faster diagnosis and treatment.
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Children with Down syndrome (DS) have an increased risk of B-cell precursor (BCP) acute lymphoblastic leukemia (ALL). The prognostic factors and outcome of DS-ALL patients treated in contemporary protocols are uncertain. We studied 653 DS-ALL patients enrolled in 16 international trials from 1995 to 2004.

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Children with Down's syndrome (DS) have an increased risk of developing acute lymphoblastic leukemia (ALL) and have a low frequency of established genetic aberrations. We aimed to determine which genetic abnormalities are involved in DS ALL. We studied the frequency and prognostic value of deletions in B-cell development genes and aberrations of janus kinase 2 (JAK2) and cytokine receptor-like factor 2 (CRLF2) using array-comparative genomic hybridization, and multiplex ligation-dependent probe amplification in a population-based cohort of 34 Dutch Childhood Oncology Group DS ALL samples.

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