Publications by authors named "T D Brandt"
Article Synopsis
- Spatial memory and orientation issues are often early signs of dementia, making early detection important for effective treatment.
- The study involved 135 participants with varying cognitive abilities, who were assessed using subjective and objective spatial orientation tests, ensuring they had normal vestibular function.
- Results showed a significant correlation between self-reported spatial discomfort and actual spatial impairment, with cognitively impaired individuals experiencing greater discomfort and higher angular deviations in tasks demanding spatial transformation.
Article Synopsis
- The ongoing GUARDIAN study aims to evaluate the feasibility and acceptability of genome sequencing as an addition to traditional newborn screening across diverse racial and ethnic groups in New York City.
- As of the interim analysis covering 4,000 newborns, 72% of approached families consented to participate, reflecting a representative sample of various racial and ethnic demographics.
- The study primarily assessed the screen-positive rate, enrollment rate, and successful sequencing completion, with a large majority of families opting to screen for both early-onset genetic conditions and additional neurodevelopmental disorders.
An earlier observational study described selected patients with acute neck pain syndrome, who experienced short bursts of cervical vertigo elicited by rapid head movements. The current study on a larger cohort of 20 patients with chronic or frequently recurring neck pain syndrome and age-matched controls focused on two major questions: (1) Can head movements in subjects with exacerbations of neck pain and restrictions of neck mobility also elicit bursts of vertigo? (2) What is the impact on postural balance measured by analysis of body sway and locomotion? A detailed questionnaire was applied, posture and gait were evaluated by use of instrumented posturography-and gait analysis with and without slow or rapid horizontal head rotations in the yaw plane with and without sight/visual input. All patients reported some or frequent episodes of dizziness in the range of seconds only elicited by rapid, not by slow head movements.
View Article and Find Full Text PDFContinuous Glucose Monitoring (CGM) not only can be used for glycemic control in chronic diseases (e.g., diabetes), but is increasingly being utilized by individuals and athletes to monitor fluctuations in training and everyday life.
View Article and Find Full Text PDFImaging endolymphatic space of the inner ear in vestibular migraine.
J Neurol Neurosurg Psychiatry
September 2024
Background: Vestibular migraine (VM), the most frequent episodic vertigo, is difficult to distinguish from Ménière's disease (MD) because reliable biomarkers are missing. The classical proof of MD was an endolymphatic hydrops (EH). However, a few intravenous gadolinium-enhanced MRI studies of the inner ear (MRI) also revealed an EH in VM.
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