Publications by authors named "T Czarnowicki"
Article Synopsis
- A population-based study analyzed cancer risk among 25,008 patients with vitiligo and 245,550 matched controls using data from Clalit Health Services from 2000-2023.
- The results showed no overall increase in cancer incidence for vitiligo patients compared to controls, with an adjusted hazard ratio of 1.00.
- Notably, patients with vitiligo had a lower risk for certain cancers, such as melanoma, lung cancer, and bladder cancer, suggesting they may not require more intensive cancer screening than the general population.
Article Synopsis
- Atopic dermatitis (AD) is an inflammatory skin condition affecting about 25% of children, often continuing into adulthood and proving challenging to control with current treatments.
- Recent research highlights the varying nature of AD among different age groups and ethnicities, indicating a need for tailored treatment approaches based on specific disease characteristics.
- Promising strategies for future AD management include exploring treatments that target the microbiome, immune responses, and neural functions to achieve better long-term symptom relief.
Fibromyalgia is a common musculoskeletal condition that affects up to 3% of the worldwide population. Its pathogenesis is not entirely clear but is thought to involve neurogenic inflammation as well as aberrations in peripheral nerves and central pain mechanisms. It is believed that the same mechanism that causes hypersensitivity and pain in patients with fibromyalgia also predisposes them to pruritus.
View Article and Find Full Text PDFInterleukin (IL)-9 is present in atopic dermatitis (AD) lesions and is considered to be mainly produced by skin-homing T cells expressing the cutaneous lymphocyte-associated antigen (CLA). However, its induction by AD-associated triggers remains unexplored. Circulating skin-tropic CLA and extracutaneous/systemic CLA memory T cells cocultured with autologous lesional epidermal cells from AD patients were activated with house dust mite (HDM) and staphylococcal enterotoxin B (SEB).
View Article and Find Full Text PDFArticle Synopsis
- A study aimed to explore the connection between socioeconomic status (SES) and the prevalence of psoriasis found that higher SES is significantly associated with increased rates of the skin condition.
- Researchers analyzed data from nearly 4.6 million patients, concluding that those in the highest SES group were 1.43 times more likely to have psoriasis than those in the lowest SES group.
- The findings suggest a correlation between SES and psoriasis prevalence, prompting the need for further research to understand the underlying factors behind this association.