Publications by authors named "T Crespo"
Purpose: To evaluate the presence of congenital hypertrophy of the retinal pigment epithelium in a large family affected by familial adenomatous polyposis and identify the causative mutation in the adenomatous polyposis coli gene. Thus, we aimed to determine the significance of congenital hypertrophy of the retinal pigment epithelium as a phenotypic marker of the disease.
Methods: A family consisting of 95 individuals was evaluated.
Assessing the usefulness of tubomanometry as a diagnostic tool in Eustachian tube dysfunction.
Eur Arch Otorhinolaryngol
October 2024
Purpose: This study aims to evaluate the validity and reliability of tubomanometry (TMM) in diagnosing obstructive Eustachian tube dysfunction (OETD) before balloon Eustachian tuboplasty (BET).
Methods: A prospective cohort study was conducted, involving 25 patients with sinonasal pathology, 75 patients with middle ear disease, and 25 healthy subjects, totaling 250 ears. All participants underwent comprehensive physical examinations, including TMM, nasal videoendoscopy, otoendoscopy, Valsalva maneuver (VM), tympanometry, and audiometry.
Oral supplementation with resveratrol improves hormonal profile and increases expression of genes associated with thermogenesis in oophorectomy mice.
Mol Cell Endocrinol
September 2024
Article Synopsis
- * Resveratrol, a compound known for its beneficial effects on metabolism, was studied to see how it affects thermogenesis markers in brown adipose tissue and various body parameters in female mice after oophorectomy (removal of ovaries).
- * After 12 weeks, resveratrol supplementation resulted in lower body weight, reduced fat levels, lower glucose and cholesterol, and improved hormonal balance, indicating its potential to enhance metabolic health in this context.
Deep Learning for Face Detection and Pain Assessment in Japanese macaques ().
J Am Assoc Lab Anim Sci
July 2024
Facial expressions have increasingly been used to assess emotional states in mammals. The recognition of pain in research animals is essential for their well-being and leads to more reliable research outcomes. Automating this process could contribute to early pain diagnosis and treatment.
View Article and Find Full Text PDFThis study evaluated the construct validity of the instrument Oral Health Literacy among diabetics. A probabilistic random sample of 239 diabetics from an infinite population answered the 10 items of the questionnaire. The structural validity was assessed by confirmatory factor analysis and goodness of fit, chi-square per degrees of freedom ratio (X2/df), comparative fit index (CFI), goodness-of-fit index (GFI), and root-mean-square error of approximation (RMSEA).
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